University of Birmingham. Researchers from the institution are starting a "ground-breaking" maternal health trial in Kenyan hospitals.

Researchers based at the University of Birmingham are starting a ground-breaking maternal health trial across 80 hospitals in South Africa, Kenya, Nigeria, Tanzania, and Sri Lanka.

The trial, called the E-MOTIVE study, aims to reduce severe b******g after birth and ultimately reduce maternal d****s and complications due to b******g by 25%.

Excessive b******g after childbirth is the leading cause of maternal d****s worldwide, mainly in low and middle-income countries (LMICs).

Arri Coomarasamy, Professor of Gynaecology and Reproductive Medicine at the University of Birmingham commented: “Every six minutes a mother d**s from childbirth-related b******g in low-resource countries, often leaving behind a young family; her newborn infant has less than a 20% chance of surviving past the first month.”

High quality childbirth care from expert healthcare professionals is available for all mothers in the UK. Tried and tested methods for dealing with severe b******g after birth are applied consistently, if a new mother starts to b***d after childbirth. 

Yet for women in LMICs, delayed detection and inconsistent treatment make excessive b******g highly dangerous. Developing a package of care to help diagnose b******g early, and treat women quickly can make the difference between life and d***h.

The study aims to generate the necessary evidence to give healthcare practitioners and policy-makers the confidence to implement and scale up the E-MOTIVE program, moving us closer to having a solution for stopping mothers from dying from b******g after childbirth.

“Doctors and midwifes often do not realise that a woman is b******g excessively – and thus the woman may not get life-saving treatment in time. The longer the delay in detection and treatment of the excessive b******g, the greater the risk of her life being lost.” said Dr Ioannis Gallos, Senior Clinical Lecturer at the University of Birmingham.

“Easy-to-implement interventions, that could be critical, are inconsistently used. Our program intends to change practice so that women get the right treatment at the right time.”

Led by Professor Arri Coomarasamy, a renowned Professor of Gynaecology and Reproductive Medicine and the Director of the WHO Collaborating Centre for Global Women’s Health, and Dr Ioannis Gallos, Senior Clinical Lecturer, the University team will conduct a global study, E-MOTIVE, to better detect and treat mothers suffering excessive b******g after childbirth. The E-MOTIVE study is supported by the Institute of Global Innovation of the University of Birmingham and a $10.9M grant from the Bill & Melinda Gates Foundation.

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